422 Pharmaceutical courses

Level 5 QLS Endorsed Course with FREE Certificate | CPD & CiQ Accredited | 150 CPD Points | Lifetime Access

When you cook a meal, you are performing chemistry. The ingredients you use and the way you prepare them can change their chemical composition and affect the taste and texture of your food. Learning Outcomes: Gain a comprehensive understanding of basic chemistry principles. Understand the fundamental concepts of matter, atoms, chemical bonding, and energy. Explore the periodic table and learn about intermolecular forces, gases, and solutions. Develop an understanding of chemical equilibrium, kinetics, acids and bases, and redox reactions. Learn about electricity and chemistry, inorganic and organic chemistry, biochemistry, nuclear chemistry, industrial chemistry, and environmental chemistry. Understand laboratory safety protocols and chemical hygiene plans. This Basic Chemistry course provides a comprehensive introduction to the fundamental principles and concepts of chemistry. The course covers a range of topics, including matter, atoms, chemical bonding, energy, the periodic table, intermolecular forces, gases, solutions, chemical equilibrium, kinetics, acids and bases, redox reactions, electricity and chemistry, inorganic and organic chemistry, biochemistry, nuclear chemistry, industrial chemistry, and environmental chemistry. Additionally, the course covers laboratory safety protocols and chemical hygiene plans. This theoretical course is perfect for those seeking to develop a deep understanding of chemistry concepts and principles. Whether you are a student studying chemistry, a professional seeking to expand your knowledge, or an individual with a personal interest in the subject, this course is designed to provide a comprehensive overview of chemistry. Certification Upon completion of the course, learners can obtain a certificate as proof of their achievement. You can receive a £4.99 PDF Certificate sent via email, a £9.99 Printed Hardcopy Certificate for delivery in the UK, or a £19.99 Printed Hardcopy Certificate for international delivery. Each option depends on individual preferences and locations. CPD 10 CPD hours / points Accredited by CPD Quality Standards Who is this course for? Students studying chemistry or related subjects. Professionals seeking to expand their knowledge of chemistry. Individuals with a personal interest in chemistry. Those looking to gain a foundational understanding of chemistry principles. Career path Chemist: £20,000 - £60,000 Chemical Engineer: £25,000 - £70,000 Materials Scientist: £25,000 - £60,000 Environmental Scientist: £20,000 - £45,000 Pharmaceutical Scientist: £20,000 - £50,000 Forensic Scientist: £20,000 - £45,000

Phlebotomy and venipuncture is a rewarding career in healthcare with good job prospects. The average salary for a phlebotomist in the UK is £23,650 per year, and the job outlook is expected to grow by 17% by 2030. Phlebotomists can work in a variety of settings, including hospitals, clinics, and blood donation centres. They are responsible for collecting blood samples for diagnostic tests, so it is a job that requires attention to detail and compassion for patients. If you are looking for a rewarding career in healthcare, phlebotomy and venipuncture is a great option. With the right skillsets, you can take your first step towards a stable and well-paying job in this growing field. Our Phlebotomy & Venipuncture course starts with the basics of Phlebotomy & Venipuncture and gradually progresses towards advanced topics. Therefore, each lesson of this Phlebotomy & Venipuncture course is intuitive and easy to understand. 6 CPD Accredited Courses Are: Course 01: Phlebotomy Course 02: Venepuncture Level 3 Course 03: Sterile Compounding Preparations Course 04: Control and Administration of Medicines Course 05: Pharmacy Technician & Assistant Course 06: Infection Control & Precautions Why would you choose the Phlebotomy & Venipuncture course: Lifetime access to Phlebotomy & Venipuncture course materials Full tutor support is available from Monday to Friday with the Phlebotomy & Venipuncture course Learn Phlebotomy & Venipuncture skills at your own pace from the comfort of your home Gain a complete understanding of the Phlebotomy & Venipuncture course Accessible, informative Phlebotomy & Venipuncture learning modules designed by experts Get 24/7 help or advice from our email and live chat teams with the Phlebotomy & Venipuncture Study Phlebotomy & Venipuncture in your own time through your computer, tablet or mobile device A 100% learning satisfaction guarantee with your Phlebotomy & Venipuncture course Course 01: Phlebotomy: This course provides comprehensive training in Phlebotomy, covering venepuncture techniques, anatomy, pre- and post-procedure protocols, and blood donation procedures. Curriculum Breakdown Module 01: Venepuncture: A Method of Phlebotomy Module 02: Anatomy and Physiology Module 03: Before Venepuncture Module 04: During Venepuncture Module 05: After Venepuncture Module 06: Venepuncture for Blood Donation Module 07: Glossary Module 08: Appendix of phlebotomy Course 02: Venepuncture Level 3: Advance your Phlebotomy skills with in-depth knowledge of blood circulation, phlebotomy equipment, routine and special blood collection procedures, and infection control. Curriculum Breakdown Module 01: Blood Circulation, Function, and Composition Module 02: Phlebotomy Equipment Module 03: Routine Venipuncture Module 04: Venipuncture Complications and Pre-Examination Variables Module 05: Special Blood Collection Procedure Module 06: Infection Control and Risk Management Course 03: Sterile Compounding Preparations: Master the principles of Phlebotomy in sterile compounding, including precautions, laminar airflow hood usage, and pharmaceutical demonstrations. Curriculum Breakdown Module 01: Introduction Module 02: Universal Precautions Module 03: The Laminar Air Flow Hood (LAF) 3 lectures Module 04: Sterile Compounding Pharmaceuticals Demonstrations Module 05: Compounding Pharmacy Math Module 06: BONUS Module 07: REVIEW OF THE STERILE COMPOUNDING PROCESS Course 04: Control and Administration of Medicines: Learn Phlebotomy essentials for effective medicine management, prescribing, and optimizing medication use. Curriculum Breakdown Module 01: Medicine Management Fundamentals Module 02: Importance of Medicine Management Module 03: Prescribing Medication Effectively Module 04: Common Problems - Pharmacological Management Module 05: Common Medicines to Use Module 06: Palliative Care Module 07: The Four Principles of Medicine Optimisation Module 08: Managing Medication in Residential Aged Care Facilities Module 09: Law and Legislation Course 05: Pharmacy Technician & Assistant: Develop skills in Phlebotomy, patient counselling, and safe dispensing practices for pharmacy technicians and assistants. Curriculum Breakdown Module 1: Introduction to Pharmacy Assistant and Pharmacy Technician Module 2: Job Role of Pharmacy Technicians Module 3: Pharmacy Assistant Patient Counselling Guide Module 4: Communication in Pharmacy Settings Module 5: The Pharmacy Team and Practices Module 6: Prescription and Dispensing in Pharmacies Module 7: Dispensing Methods, EPS, Minimising Dispensing Errors in Pharmacies Module 8: Inventory Control and Management in Pharmacies Module 9: Standard Operating Procedures (SOPs) Module 10: Health and Safety Risks Assessment and Pharmaceutical Terminology Course 06: Infection Control & Precautions: Understand Phlebotomy's role in infection prevention, control policies, and immunization strategies in healthcare settings. Curriculum Breakdown Module 01: Infection Prevention and Control Policy in the UK Module 02: Principles of Prevention and Control of Infection Module 03: Immunization Module 04: Infections Spread by Food and Water Module 05: Infections Spread by Animals and Insects and Less Common Infections Found in the UK Module 06: Infections & Diseases Spread by Person-to-Person Contact Module 07: Infections Spread by Sexual Contact Module 08: Infections Spread by Blood and Body Fluids CPD 60 CPD hours / points Accredited by CPD Quality Standards Who is this course for? The Phlebotomy & Venipuncture course helps aspiring professionals who want to obtain the knowledge and familiarise themselves with the skillsets to pursue a career in Phlebotomy & Venipuncture. It is also great for professionals who are already working in Phlebotomy & Venipuncture and want to get promoted at work. Requirements To enrol in this Phlebotomy & Venipuncture course, all you need is a basic understanding of the English Language and an internet connection. Career path The Phlebotomy & Venipuncture course will enhance your knowledge and improve your confidence. Phlebotomy Technician Medical Laboratory Assistant Clinical Support Worker Healthcare Assistant Phlebotomy Supervisor/Team Lead Certificates CPD Accredited PDF Certificate Digital certificate - Included 6 CPD Accredited PDF Certificate

Pharmacology | Paramedicine Study | Nurse Prescribing & Medicine Management | Medication Administration | Substance Misuse | Medical Transcription | Lab Analyst and Laboratory Skills | Health and Social Care UK | Medical Law and Much More... If you have a passion for science and an interest in medicine, then pharmacy may be the ideal pathway for you. The other perk of this particular field is that the salaries usually are pretty good. With the UK facing the COVID crisis, there is a high demand for personnel in the pharmacology sector too! Our pharmacology bundle has been created to assist you in taking your first steps toward pharmacology by understanding the foundations. Learn the fundamentals behind how drugs impact the body - and how doctors treat real patients. Furthermore, gain knowledge on chemotherapy, injury and infection control, medicine management, prescribing for adults and children, medical reports, medical law, and much more. Along with thiscourse, you will get 10 other premium courses. Also, you will get an original Hardcopy and PDF certificate for the title course and a student ID card absolutely free. What other courses are included with this bundle? Course 01: Pharmacology Course 02: Medical Law Course 03: Control and Administration of Medicines Online Training Course Course 04: Human Anatomy and Physiology Course 05: Diploma In Microbiology Course 06: Biomedical Science Course 07: Genetics Course 08: Lab Analyst Training Course 09: Clinical Observations Skills Course 10: Public Health Course 11: Infection Prevention Training So, enrol now to advance your career! Benefits you'll get choosing Apex Learning for this course: One payment, but lifetime access to 11 CPD courses Certificate, student ID for the title course included in a one-time fee Full tutor support available from Monday to Friday Free up your time - don't waste time and money travelling for classes Accessible, informative modules taught by expert instructors Learn at your ease - anytime, from anywhere Study the course from your computer, tablet or mobile device CPD accredited course - improve the chance of gaining professional skills Gain valuable and in-demand skills without leaving your home. How will I get my Certificate? After successfully completing the course you will be able to order your CPD Accredited Certificates (PDF + Hard Copy) as proof of your achievement. PDF Certificate: Free (Previously it was £6*11 = £66) Hard Copy Certificate: Free (For The Title Course: Previously it was £10) If you want to get hardcopy certificates for other courses, generally you have to pay £20 for each. But this Fall, Apex Learning is offering a Flat 50% discount on hard copy certificates, and you can get each for just £10! P.S. The delivery charge inside the U.K. is £3.99 and the international students have to pay £9.99. Course Curriculum Bundle Part 01: Course 1: Module 01 Fundamental Principles of Pharmacology Pharmacology Pharmacodynamics Pharmacokinetics Pharmacogenomics Drug Toxicity Module 02 Drug Development and Regulation Drug development Drug Discovery Preclinical Development Clinical Drug Evaluation Regulatory Approval Module 03 Neuropharmacology The Nervous System (CNS) The Organisation of CNS Cellular Communication Pharmacology of Ion Channel Neurodegenerative Diseases Anxiolytic and Hypnotic Module 04 Cardiovascular Pharmacology Cardiovascular Pharmacology Hypertension Diuretics Drugs Sympatholytic Drugs Angiotensin Inhibitors Antiadrenergic Drugs Vasodilators Module 05 Endocrine Pharmacology Endocrine Pharmacology Hormones Hypothalamus and Pituitary Gland Thyroid Gland Adrenal Cortex Endocrine Pancreas and Glucose Homeostasis Module 06 Chemotherapy Chemotherapy Cancer Chemotherapy Antimicrobial Therapy Module 07 Inflammation and Immune Pharmacology Immune System Immunosuppression Inflammation Histamine Haematopoiesis Module 08 Toxicology Toxicology Environmental toxicology Acute Toxicology Chronic Toxicology Alcohol Abuse Course 02: Medical Law An Introduction to Medical Law Legislation on Access to Health, Medical Report, Treatment Legislation on Adult Support Legislation on Public Health and Health Service (Part 1) Legislation on Public Health and Health Service (Part 2) Legislation on Public Health and Health Service (Part 3) Legislation on Public Health and Health Service (Part 4) Legislation on Coronavirus Legislation on Mental Health (Part 1) Legislation on Mental Health (Part 2) Legislation on Abortion Other Legislation (Part 1) Other Legislation (Part 2) Course 03: Control and Administration of Medicines Online Training Course Medicine Management Fundamentals Importance of Medicine Management Prescribing Medication Effectively Common Problems - Pharmacological Management Common Medicines to Use Palliative Care The Four Principles of Medicine Optimisation Managing Medication in Residential Aged Care Facilities (RACFs) Law and Legislation Course 04: Human Anatomy and Physiology Human Body Vocabulary with Pictures Equipment, Instruments and Lab Tests Acronyms and Abbreviation Digestive System Cardiovascular System Blood and Immunity System Respiratory System Musculoskeletal System Central Nervous System Course 05: Diploma In Microbiology Introduction to Microbiology Cell Structure and Organisation The Chemical Metabolism Microbial Growth Controlling Microbial Diversity Prokaryote Diversity Microbial Diversity Eukaryote Diversity Viruses, Viroids, and Prions Interactions between Microbes and Humans Human Microbial Diseases Immunity Vaccines and Antimicrobial Agents Microorganisms in the Environment Industrial and Food Microbiology Course 06: Biomedical Science Introduction to Biomedical Science Genetics and Biochemistry Microbiology and Cell Biology Biochemical Engineering and Enzyme Discovery Toxicology, Pharmaceuticals and Fine Chemicals Systems and Synthetic Biology Global Health Challenges Course 07: Genetics Fundamental Concepts of Genetics Genetics and Genomics Genetic Disorders Genetic Counselling Application of Genetics Knowledge Course 08: Lab Analyst Training Introduction to the Course Medical Laboratory Services Laboratory Equipments (Part-01) Laboratory Equipments (Part-02) Microscope and How to Use It Solutions Used in Clinical/Medical Laboratory Sterilisation, Disinfection and Decontamination Basic Haematology Basic Haemostasis (Coagulation) Basic Immunology and Immunohematology Urinalysis Basic Clinical Chemistry Basic Clinical Microbiology Basic Parasitology Laboratory Accidents and Safety Quality Assurance Course 09: Clinical Observations Skills Introduction to Clinical Observation and Clinical Carer Legal Standards and Professional Aspects of Ethical Practice Patient's Condition Observation Clinical Management Observation Technical Clinical Method Observation Medicine and Dispensaries Observation Health Safety and Hygiene Course 10: Public Health Introduction to Public Health Principles of Public Health Understanding Epidemiology Disease Control Understanding Measures of Disease Frequency Maternity and Childbirth Environment and Public Health Health System and Policy Public Health and Ethics Course 11: Infection Prevention Training Infection Prevention and Control Policy in the UK Principles of Prevention and Control of Infection Immunization Infections Spread by Food and Water Infections Spread by Animals and Insects, and Less Common Infections Found in the UK Infections & Diseases Spread by Person-to-Person Contact Infections Spread by Sexual Contact Infections Spread by Blood and Body Fluids CPD 115 CPD hours / points Accredited by CPD Quality Standards Who is this course for? Anyone from any background can enrol in this Pharmacology bundle. Persons with similar professions can also refresh or strengthen their skills by enrolling in this course. Students can take this course to gather professional knowledge besides their study or for the future. P.S. Completing this course does not imply that you are qualified to work as a Pharmacy Technician or Pharmacist. If you are seeking a course that fits The General Pharmaceutical Council's standards, please contact The General Pharmaceutical Council. Requirements Our course is fully compatible with PC's, Mac's, Laptop, Tablet and Smartphone devices. This course has been designed to be fully compatible with tablets and smartphones so you can access your course on Wi-Fi, 3G or 4G. There is no time limit for completing this course, it can be studied in your own time at your own pace. Career path This comprehensive bundle is ideal for aspiring professionals, and those who are new to their role who wish to gain theoretical knowledge to kickstart their careers. Toxicologist Pharmacist Veterinary Pharmacologist Academic Researcher Analytical Chemist Research Scientist Medical Sales Representative Certificates Certificate of completion Digital certificate - Included Certificate of completion Hard copy certificate - Included You will get the Hard Copy certificate for the title course (Pharmacology) absolutely Free! Other Hard Copy certificates are available for £10 each. Please Note: The delivery charge inside the UK is £3.99, and the international students must pay a £9.99 shipping cost.

Course Overview Know how to use 'Xhosa' correctly when dealing with sick or injured people in a clinical environment with this unique course on how to Learn IsiXhosa for Healthcare: Pharmacist. Using proven techniques and expert guidance, you will be taught how to use and understand the language proficiently for medical terms, empowering you to diagnose conditions and potentially save lives. This innovative IsiXhosa tutorial offers the best way to learn the terminology and questioning methods needed to excel in this sector of healthcare and linguistics. You will be taught how to gain the trust of IsiXhosa-speaking patients or customers, attain knowledge about their health or concerns, and provide excellent pharmaceutical service. From greeting to prescribing, this is a full learning curve in language specialisation. This is a unique chance for established and student pharmacists to master this language and become aware of its nuances and flexibility in the healthcare trade. This best selling Learn IsiXhosa for Healthcare: Pharmacist has been developed by industry professionals and has already been completed by hundreds of satisfied students. This in-depth Learn IsiXhosa for Healthcare: Pharmacist is suitable for anyone who wants to build their professional skill set and improve their expert knowledge. The Learn IsiXhosa for Healthcare: Pharmacist is CPD-accredited, so you can be confident you're completing a quality training course will boost your CV and enhance your career potential. The Learn IsiXhosa for Healthcare: Pharmacist is made up of several information-packed modules which break down each topic into bite-sized chunks to ensure you understand and retain everything you learn. After successfully completing the Learn IsiXhosa for Healthcare: Pharmacist, you will be awarded a certificate of completion as proof of your new skills. If you are looking to pursue a new career and want to build your professional skills to excel in your chosen field, the certificate of completion from the Learn IsiXhosa for Healthcare: Pharmacist will help you stand out from the crowd. You can also validate your certification on our website. We know that you are busy and that time is precious, so we have designed the Learn IsiXhosa for Healthcare: Pharmacist to be completed at your own pace, whether that's part-time or full-time. Get full course access upon registration and access the course materials from anywhere in the world, at any time, from any internet-enabled device.  Our experienced tutors are here to support you through the entire learning process and answer any queries you may have via email.

Description Neuroscience Diploma  In biology, a sub-field known as neuroscience is concerned with analysing the structure of our nervous system, how it functions, and how it has evolved. Neuroscience is a constantly changing discipline; however, its contents may be categorised into various branches, such as clinical, cognitive, developmental, and computational neuroscience. It is an interdisciplinary study closely associated with physics, chemistry, medicine, computer science, linguistics, philosophy, and engineering. Neuroscientists concentrate on analysing the nervous system at both the cellular and operational levels to see how it impacts behavioural events and patterns. Their research may include hypothesising theories or conducting laboratory experiments using special techniques, tools, or computer simulations. In the Neuroscience Diploma course, students will learn how to examine the nervous system, including its structure and biological processes, and how these apply to the development of artificial intelligence systems. There are different specialisations that people can choose within the field, such as behavioural and cognitive, affective, molecular, neuroimaging, neurolinguistics, neurophysiology, social neuroscience, and many more. Most jobs available for someone with a background in neuroscience would mostly be in the healthcare and pharmaceutical industries, with companies that handle communication and information science, and with organisations that manage public health structures. Traditionally, the discipline of neuroscience had birthed professionals like neuroanatomists, neurologists, neuro-pharmacologists, neurological surgeons, technicians dealing with electro-neurodiagnostic machines, and psychiatrists. Students will learn about the nervous system's neurophysiology and functional organisation to better understand human behaviour. Find out how neural systems work in our brain and spinal cord to help us detect things, move different parts of our bodies, store information we obtain from our senses, relate it to emotions, and analyse it using various cognitive processes. The main objective of this Neuroscience Diploma course is to help students establish the foundational knowledge that will help them understand how sensations may be impaired, how injuries may lead to physical or cognitive difficulties and other diseases or malfunctioning of the nervous system. Through the Neuroscience Diploma course, you will come to know how neurons transmit information among themselves using electrical impulses. This course is an introductory course on the functioning and organisation of the central nervous system. Various topics will be covered, including the structure of neurons, the neurotransmitters in the brain, electrical impulses as signals, motor and sensory systems, the neurobiological aspect of human development, simple circuits, learning, and human behaviour. What you will learn   1:A Walkthrough of Your Nervous System  2:Know About Your Brain and Spinal Cord  3:Sensory Neuron and The Skin  4:Role of Eye in Vision  5:The Auditory System  6:Taste and Smell 7:Movement 8:Know About Intelligence Emotions and Consciousness 9:The Role of Brain in Language 10:Role of Brain in Learning and Memory  Course Outcomes After completing the course, you will receive a diploma certificate and an academic transcript from Elearn college. Assessment Each unit concludes with a multiple-choice examination. This exercise will help you recall the major aspects covered in the unit and help you ensure that you have not missed anything important in the unit. The results are readily available, which will help you see your mistakes and look at the topic once again. If the result is satisfactory, it is a green light for you to proceed to the next chapter. Accreditation Elearn College is a registered Ed-tech company under the UK Register of Learning( Ref No:10062668). After completing a course, you will be able to download the certificate and the transcript of the course from the website. For the learners who require a hard copy of the certificate and transcript, we will post it for them for an additional charge.

2 QLS Endorsed Course | CPD Certified | Free PDF + Hardcopy Certificates | 80 CPD Points | Lifetime Access

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Overview This comprehensive course on Dementia Awareness will deepen your understanding on this topic. After successful completion of this course you can acquire the required skills in this sector. This Dementia Awareness comes with accredited certification from CPD, which will enhance your CV and make you worthy in the job market. So enrol in this course today to fast track your career ladder. How will I get my certificate? You may have to take a quiz or a written test online during or after the course. After successfully completing the course, you will be eligible for the certificate. Who is This course for? There is no experience or previous qualifications required for enrolment on this Dementia Awareness. It is available to all students, of all academic backgrounds. Requirements Our Dementia Awareness is fully compatible with PC's, Mac's, Laptop, Tablet and Smartphone devices. This course has been designed to be fully compatible with tablets and smartphones so you can access your course on Wi-Fi, 3G or 4G. There is no time limit for completing this course, it can be studied in your own time at your own pace. Career Path Learning this new skill will help you to advance in your career. It will diversify your job options and help you develop new techniques to keep up with the fast-changing world. This skillset will help you to- Open doors of opportunities Increase your adaptability Keep you relevant Boost confidence And much more! Course Curriculum 11 sections • 11 lectures • 03:47:00 total length •Defining Dementia: 00:12:00 •The Brain and How Dementia Affects It: 00:20:00 •Types of Dementia: 00:30:00 •Stages of Dementia: 00:35:00 •Assessing Dementia: 00:14:00 •Pharmaceutical Treatment for Dementia: 00:25:00 •Psychological Treatment for Dementia: 00:30:00 •Raising Awareness and Preventing Dementia: 00:35:00 •Caregiving for Dementia: 00:10:00 •Dementia Care Acts and Legislation: 00:16:00 •Assignment - Dementia Awareness: 00:00:00

Overview This comprehensive course on Good Manufacturing Practice (GMP) will deepen your understanding on this topic. After successful completion of this course you can acquire the required skills in this sector. This Good Manufacturing Practice (GMP) comes with accredited certification from CPD, which will enhance your CV and make you worthy in the job market. So enrol in this course today to fast track your career ladder. How will I get my certificate? You may have to take a quiz or a written test online during or after the course. After successfully completing the course, you will be eligible for the certificate. Who is This course for? There is no experience or previous qualifications required for enrolment on this Good Manufacturing Practice (GMP). It is available to all students, of all academic backgrounds. Requirements Our Good Manufacturing Practice (GMP) is fully compatible with PC's, Mac's, Laptop, Tablet and Smartphone devices. This course has been designed to be fully compatible with tablets and smartphones so you can access your course on Wi-Fi, 3G or 4G. There is no time limit for completing this course, it can be studied in your own time at your own pace. Career Path Learning this new skill will help you to advance in your career. It will diversify your job options and help you develop new techniques to keep up with the fast-changing world. This skillset will help you to- Open doors of opportunities Increase your adaptability Keep you relevant Boost confidence And much more! Course Curriculum 9 sections • 9 lectures • 05:38:00 total length •Basic Concept of GMP and Safety Regulations: 00:41:00 •Good and Bad Manufacturing Practice: 00:44:00 •Preventing and Controlling Contamination: 00:37:00 •Maintenance and Hygiene: 00:41:00 •GMP for Pharmaceutical Industry: 00:56:00 •GMP for Food Industry: 00:34:00 •GMP for Cosmetics Industry: 00:54:00 •IT Applications on GMP: 00:31:00 •Assignment - Good Manufacturing Practice (GMP): 00:00:00