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254 Cardiovascular courses delivered On Demand

Anatomy and physiology Training Course

By Compete High

🔬 Embark on a Journey of Discovery: Anatomy and Physiology Training Course! 🌐 Are you ready to unravel the mysteries of the human body? Dive into our Anatomy and Physiology Training Course, a comprehensive program meticulously designed to deepen your understanding of the intricacies of human anatomy and physiology. Join us on a journey where science meets discovery, and turn your passion for the human body into a foundation for a fulfilling career. 🌟 Module 1: Introduction to Anatomy and Physiology Embark on your exploration with Module 1, providing a comprehensive introduction to the fascinating world of anatomy and physiology. Lay the groundwork for understanding the structure and function of the human body. Delve into the essential concepts, terminology, and the interconnectedness of various bodily systems. 💀 Module 2: Skeletal System Enter the framework of the body with Module 2, dedicated to the skeletal system. Explore the bones, joints, and connective tissues that form the foundation of our physical structure. Understand the role of the skeletal system in providing support, protection, and facilitating movement. 💪 Module 3: Muscular System Dive into the powerhouse of movement with Module 3, focusing on the muscular system. Explore the various muscles, their functions, and the mechanics of muscle contraction. Gain insights into how muscles work in harmony to produce coordinated movement and maintain posture. ️ Module 4: Cardiovascular System Explore the body's intricate transport system with Module 4, dedicated to the cardiovascular system. Examine the heart, blood vessels, and blood components, understanding how they work together to circulate oxygen, nutrients, and waste products throughout the body. Uncover the complexities of cardiovascular health and functionality. 🌬️ Module 5: Respiratory System Venture into the breath of life with Module 5, focusing on the respiratory system. Explore the anatomy of the lungs, airways, and the mechanics of breathing. Understand the exchange of oxygen and carbon dioxide, and how the respiratory system plays a crucial role in maintaining homeostasis. 🌟 Why Choose Our Anatomy and Physiology Training Course? Expert Instruction: Learn from experienced anatomists and physiologists with a deep understanding of the human body. Interactive Learning: Engage in virtual dissections, simulations, and practical exercises to reinforce your theoretical knowledge. Clinical Applications: Understand the practical applications of anatomy and physiology in various healthcare and wellness fields. Career Pathways: Develop a strong foundation for careers in healthcare, fitness, research, and education. Don't miss the opportunity to unlock the secrets of the human body! Enroll now in the Anatomy and Physiology Training Course and pave the way for a career where your in-depth knowledge of the body becomes a foundation for making a positive impact. Your journey into the wonders of anatomy and physiology begins here! 🔬✨🎓 Course Curriculum Module 1_ Introduction to Anatomy and Physiology. Introduction to Anatomy and Physiology. 00:00 Module 2_ Skeletal System. Skeletal System. 00:00 Module 3_ Muscular System. Muscular System. 00:00 Module 4_ Cardiovascular System. Cardiovascular System. 00:00 Module 5_ Respiratory System. Respiratory System. 00:00

Anatomy and physiology Training Course
Delivered Online On Demand5 hours
£25

Principles of Pharmacology

By Online Training Academy

Unlock the science behind drug interactions and therapeutic principles with our comprehensive "Principles of Pharmacology" course. Perfect for aspiring pharmacologists, healthcare professionals, and students, this course delves into essential topics essential for understanding the impact of medications on the human body. Key Features: CPD Certified Free Certificate from Reed CIQ Approved Developed by Specialist Lifetime Access In the "Principles of Pharmacology" course, learners will explore essential concepts and practices in the study of how drugs affect the body. They will gain a deep understanding of how medications are developed, regulated, and used in treating various health conditions. The course covers the effects of drugs on the nervous system, heart, hormones, and immune responses, providing insights into their mechanisms and applications. Students will also learn about the specific pharmacological treatments for cancer and understand the principles of toxicology, including how substances can be harmful to biological systems. This comprehensive curriculum equips learners with crucial knowledge to understand drug actions, their therapeutic uses, and potential risks, preparing them to contribute effectively in fields related to healthcare, research, and pharmaceutical industries. Course Curriculum Module 01: Fundamental Principles of Pharmacology Module 02: Drug Development and Regulation Module 03: Neuropharmacology Module 04: Cardiovascular Pharmacology Module 05: Endocrine Pharmacology Module 06: Inflammation and Immune Pharmacology Module 07: Chemotherapy Module 08: Toxicology Learning Outcomes: Understand fundamental principles of pharmacology and their applications in healthcare. Analyze the process of drug development and the regulatory framework. Explain neuropharmacology and its implications in neurological disorders treatment. Evaluate cardiovascular pharmacology and its impact on heart health management. Discuss endocrine pharmacology and its role in hormonal balance maintenance. Explore inflammation and immune pharmacology in the context of immune system regulation. CPD 10 CPD hours / points Accredited by CPD Quality Standards Principles of Pharmacology 1:33:31 1: Module 01: Fundamental Principles of Pharmacology 13:50 2: Module 02: Drug Development and Regulation 09:27 3: Module 03: Neuropharmacology 09:35 4: Module 04: Cardiovascular Pharmacology 12:25 5: Module 05: Endocrine Pharmacology 14:46 6: Module 06: Inflammation and Immune Pharmacology 09:27 7: Module 07: Chemotherapy 11:50 8: Module 08: Toxicology 11:11 9: CPD Certificate - Free 01:00 Who is this course for? Pharmacology students seeking foundational knowledge. Healthcare professionals expanding their understanding of pharmacological principles. Researchers focusing on drug development and regulatory aspects. Medical professionals specializing in neurological or cardiovascular fields. Biomedical scientists interested in pharmacological research. Career path Pharmacologist Pharmaceutical Research Scientist Clinical Trial Coordinator Cardiovascular Pharmacologist Neuropharmacologist Toxicologist Certificates Digital certificate Digital certificate - Included Reed Courses Certificate of Completion Digital certificate - Included Will be downloadable when all lectures have been completed.

Principles of Pharmacology
Delivered Online On Demand2 minutes
£12

Principles of Pharmacology

By Online Training Academy

Unlock the science behind drug interactions and therapeutic principles with our comprehensive "Principles of Pharmacology" course. Perfect for aspiring pharmacologists, healthcare professionals, and students, this course delves into essential topics essential for understanding the impact of medications on the human body. Key Features: CPD Certified Free Certificate from Reed CIQ Approved Developed by Specialist Lifetime Access In the "Principles of Pharmacology" course, learners will explore essential concepts and practices in the study of how drugs affect the body. They will gain a deep understanding of how medications are developed, regulated, and used in treating various health conditions. The course covers the effects of drugs on the nervous system, heart, hormones, and immune responses, providing insights into their mechanisms and applications. Students will also learn about the specific pharmacological treatments for cancer and understand the principles of toxicology, including how substances can be harmful to biological systems. This comprehensive curriculum equips learners with crucial knowledge to understand drug actions, their therapeutic uses, and potential risks, preparing them to contribute effectively in fields related to healthcare, research, and pharmaceutical industries. Course Curriculum Module 01: Fundamental Principles of Pharmacology Module 02: Drug Development and Regulation Module 03: Neuropharmacology Module 04: Cardiovascular Pharmacology Module 05: Endocrine Pharmacology Module 06: Inflammation and Immune Pharmacology Module 07: Chemotherapy Module 08: Toxicology Learning Outcomes: Understand fundamental principles of pharmacology and their applications in healthcare. Analyze the process of drug development and the regulatory framework. Explain neuropharmacology and its implications in neurological disorders treatment. Evaluate cardiovascular pharmacology and its impact on heart health management. Discuss endocrine pharmacology and its role in hormonal balance maintenance. Explore inflammation and immune pharmacology in the context of immune system regulation. CPD 10 CPD hours / points Accredited by CPD Quality Standards Principles of Pharmacology 1:33:31 1: Module 01: Fundamental Principles of Pharmacology 13:50 2: Module 02: Drug Development and Regulation 09:27 3: Module 03: Neuropharmacology 09:35 4: Module 04: Cardiovascular Pharmacology 12:25 5: Module 05: Endocrine Pharmacology 14:46 6: Module 06: Inflammation and Immune Pharmacology 09:27 7: Module 07: Chemotherapy 11:50 8: Module 08: Toxicology 11:11 9: CPD Certificate - Free 01:00 Who is this course for? Pharmacology students seeking foundational knowledge. Healthcare professionals expanding their understanding of pharmacological principles. Researchers focusing on drug development and regulatory aspects. Medical professionals specializing in neurological or cardiovascular fields. Biomedical scientists interested in pharmacological research. Career path Pharmacologist Pharmaceutical Research Scientist Clinical Trial Coordinator Cardiovascular Pharmacologist Neuropharmacologist Toxicologist Certificates Digital certificate Digital certificate - Included Reed Courses Certificate of Completion Digital certificate - Included Will be downloadable when all lectures have been completed.

Principles of Pharmacology
Delivered Online On Demand1 hour 36 minutes
£12

Principles of Pharmacology

By Online Training Academy

Unlock the science behind drug interactions and therapeutic principles with our comprehensive "Principles of Pharmacology" course. Perfect for aspiring pharmacologists, healthcare professionals, and students, this course delves into essential topics essential for understanding the impact of medications on the human body. Key Features: CPD Certified Free Certificate from Reed CIQ Approved Developed by Specialist Lifetime Access In the "Principles of Pharmacology" course, learners will explore essential concepts and practices in the study of how drugs affect the body. They will gain a deep understanding of how medications are developed, regulated, and used in treating various health conditions. The course covers the effects of drugs on the nervous system, heart, hormones, and immune responses, providing insights into their mechanisms and applications. Students will also learn about the specific pharmacological treatments for cancer and understand the principles of toxicology, including how substances can be harmful to biological systems. This comprehensive curriculum equips learners with crucial knowledge to understand drug actions, their therapeutic uses, and potential risks, preparing them to contribute effectively in fields related to healthcare, research, and pharmaceutical industries. Course Curriculum Module 01: Fundamental Principles of Pharmacology Module 02: Drug Development and Regulation Module 03: Neuropharmacology Module 04: Cardiovascular Pharmacology Module 05: Endocrine Pharmacology Module 06: Inflammation and Immune Pharmacology Module 07: Chemotherapy Module 08: Toxicology Learning Outcomes: Understand fundamental principles of pharmacology and their applications in healthcare. Analyze the process of drug development and the regulatory framework. Explain neuropharmacology and its implications in neurological disorders treatment. Evaluate cardiovascular pharmacology and its impact on heart health management. Discuss endocrine pharmacology and its role in hormonal balance maintenance. Explore inflammation and immune pharmacology in the context of immune system regulation. CPD 10 CPD hours / points Accredited by CPD Quality Standards Principles of Pharmacology 1:33:31 1: Module 01: Fundamental Principles of Pharmacology 13:50 2: Module 02: Drug Development and Regulation 09:27 3: Module 03: Neuropharmacology 09:35 4: Module 04: Cardiovascular Pharmacology 12:25 5: Module 05: Endocrine Pharmacology 14:46 6: Module 06: Inflammation and Immune Pharmacology 09:27 7: Module 07: Chemotherapy 11:50 8: Module 08: Toxicology 11:11 9: CPD Certificate - Free 01:00 Who is this course for? Pharmacology students seeking foundational knowledge. Healthcare professionals expanding their understanding of pharmacological principles. Researchers focusing on drug development and regulatory aspects. Medical professionals specializing in neurological or cardiovascular fields. Biomedical scientists interested in pharmacological research. Career path Pharmacologist Pharmaceutical Research Scientist Clinical Trial Coordinator Cardiovascular Pharmacologist Neuropharmacologist Toxicologist Certificates Digital certificate Digital certificate - Included Reed Courses Certificate of Completion Digital certificate - Included Will be downloadable when all lectures have been completed.

Principles of Pharmacology
Delivered Online On Demand1 hour 36 minutes
£12

English for Healthcare Part - 2

By iStudy UK

Course Description Get instant knowledge from this bite-sized English for Healthcare Part - 2 course. This course is very short and you can complete it within a very short time. In this English for Healthcare Part - 2 course you will get fundamental ideas of English for healthcare, the key understanding of the musculoskeletal system, immunity system and so on. Enrol in this course today and start your instant first step towards learning about the cardiovascular system. Learn faster for instant implementation. Learning Outcome Familiarise with the respiratory system Understand the musculoskeletal system Understand the blood and immunity system Learn about the cardiovascular system How Much Do Health Care Assistants Earn? Senior - £51,000 (Apprx.) Average - £29,000 (Apprx.) Starting - £16,000 (Apprx.) Requirement Our English for Healthcare Part - 2 is fully compatible with any kind of device. Whether you are using Windows computer, Mac, smartphones or tablets, you will get the same experience while learning. Besides that, you will be able to access the course with any kind of internet connection from anywhere at any time without any kind of limitation. English for Healthcare Part - 2 Module 01: Cardiovascular System 00:22:00 Module 02: Blood and Immunity System 00:17:00 Module 03: Respiratory System 00:19:00 Module 04: Musculoskeletal System 00:19:00 Assignment Assignment - English for Healthcare Part - 2 00:00:00

English for Healthcare Part - 2
Delivered Online On Demand1 hour 17 minutes
£25

Resuscitation & Life Support Training

4.3(43)

By John Academy

Overview The right action at the right take can draw the line between life and death. That's why it is so important to learn the basic life support skills. Our Resuscitation & Life Support Training is the perfect place where you can learn these valuable life-saving skills. This comprehensive course will provide you with an in-depth understanding of resuscitation and life support. Here, you will get primary to advanced-level training on life support. The course will introduce you to the process of cardiovascular life support. In addition, you will acquire the skills for airway management and be able to use Automated External Defibrillators. After the completion of the course, you will receive a certificate of achievement accredited by CPDQS. This certificate will increase your value in the healthcare sector. Enrol now! Course Preview Learning Outcomes Understand the concepts of resuscitation Learn the process of providing basic life support Deepen your understanding of the ABCDE approach Know how the basics of cardiovascular support Build your expertise in airway management and post-resuscitation care Why Take This Course From John Academy? Affordable, well-structured and high-quality e-learning study materials Engaging tutorial videos, materials from the industry-leading experts Opportunity to study in a user-friendly, advanced online learning platform Efficient exam systems for the assessment and instant result Earn UK & internationally recognised accredited qualification Easily access the course content on mobile, tablet, or desktop from anywhere, anytime Excellent career advancement opportunities Get 24/7 student support via email. What Skills Will You Learn from This Course? Life Support Cardiovascular life support Airway management Who Should Take This Resuscitation & Life Support Training? Whether you're an existing practitioner or an aspiring professional, this course is an ideal training opportunity. It will elevate your expertise and boost your CV with key skills and a recognised qualification attesting to your knowledge. Are There Any Entry Requirements? This Resuscitation & Life Support Training course is available to all learners of all academic backgrounds. But learners should be aged 16 or over to undertake the qualification. And a good understanding of the English language, numeracy, and ICT will be helpful. Certificate of Achievement After completing this course successfully, you will be able to obtain an Accredited Certificate of Achievement. Certificates & Transcripts can be obtained either in Hardcopy at £14.99 or in PDF format at £11.99. Career Path​ This exclusive Resuscitation & Life Support Training course will equip you with effective skills and abilities and help you explore career paths such as  First-aider Paramedic Health Care worker Module 01: Introduction to Resuscitation and Basic Life Support Introduction to Resuscitation and Basic Life Support 00:13:00 Module 02: Prevention and Preparation Prevention and Preparation 00:14:00 Module 03: Basic and Advanced Life Support Basic and Advanced Life Support 00:14:00 Module 04: Advanced Cardiovascular Life Support (ACLS) Advanced Cardiovascular Life Support (ACLS) 00:12:00 Module 05: Airway Management Airway Management 00:13:00 Module 06: Defibrillation Defibrillation 00:14:00 Module 07: Post-Resuscitation Care Post-Resuscitation Care 00:14:00 Certificate and Transcript Order Your Certificates and Transcripts 00:00:00

Resuscitation & Life Support Training
Delivered Online On Demand1 hour 34 minutes
£24.99

Exercise Physiology Online Course: Foundations

4.3(43)

By John Academy

Discover the intricate mechanisms behind human movement and physical performance in our comprehensive online course. Explore anatomy, bioenergetics, cardiovascular health, and training principles. Perfect for aspiring coaches, trainers, and sports science enthusiasts. Enroll now and unlock the secrets to optimizing athletic potential!

Exercise Physiology Online Course: Foundations
Delivered Online On Demand2 hours
£23.99

Gym Instructor Course: Your Path to a Rewarding Fitness Career

4.3(43)

By John Academy

Transform your passion for fitness into a fulfilling career with our Gym Instructor Course. Master the fundamentals of training, anatomy, equipment usage, and client assessment. Gain expertise in cardiovascular workouts, safety, injury prevention, and nutrition. Enroll now to embark on a rewarding journey towards becoming a certified gym instructor and making a positive impact on others' health and well-being.

Gym Instructor Course: Your Path to a Rewarding Fitness Career
Delivered Online On Demand
£23.99

CardioWellness: Nurturing Heart Health

By Compete High

🌟 CardioWellness: Nurturing Heart Health Online Course 🌟 Unlock the Secrets to a Healthier Heart and a Happier Life! Are you ready to take control of your heart health and embrace a life full of vitality? Introducing our groundbreaking online course: CardioWellness - where we delve deep into the intricacies of heart health to empower you with knowledge, strategies, and practical tips to nurture your most vital organ.   🔍 Course Overview: Module 1: Introduction & First Concepts Lay the foundation for a heart-healthy journey. Understand the basics of cardiovascular health, the role of the heart, and how small lifestyle changes can make a significant impact. Module 2: What Is A Heart Attack & Complications Knowledge is power. Uncover the mysteries behind heart attacks, their causes, and potential complications. Arm yourself with information to protect your heart and your loved ones. Module 3: Emergency Care For A Heart Attack Be a lifesaver! Learn crucial, life-saving techniques to provide immediate care in case of a heart attack. Time is of the essence, and this module equips you with the skills to act swiftly and effectively. Module 4: Risk Factors & Lifestyle Choices Prevention is key. Identify the risk factors contributing to heart issues and explore lifestyle choices that can positively impact your heart health. Discover how to make informed decisions for a heart-friendly lifestyle. Module 5: Heart Remedies Natural solutions for a healthier heart. Explore holistic approaches and remedies to support cardiovascular health. From nutrition to exercise, this module provides actionable steps to enhance your heart's well-being. Module 6: Final Tips & Suggestions Seal the deal with invaluable tips and suggestions for a heart-healthy future. Combine your newfound knowledge with practical advice to create lasting habits that will keep your heart thriving.   🎓 Why CardioWellness? Expert Guidance: Learn from experienced professionals in the field of cardiology. Comprehensive Curriculum: Covering everything from prevention to emergency care. Practical Insights: Gain actionable tips to implement in your daily life. Convenient Learning: Access the course from the comfort of your home, on your schedule.   💖 Invest in Your Heart Health Today! Your heart is your most precious asset - don't wait until it's too late. Enroll in CardioWellness now and embark on a journey to a healthier, happier heart. Your future self will thank you!   🚀 Join Now and Prioritize Your Cardiovascular Well-being! [Disclaimer: Always consult with a healthcare professional before making significant lifestyle changes or starting a new health regimen.] Course Curriculum Introduction & First Concepts Introduction 00:00 What Is A Heart Attack & Complications What Is A Heart Attack 00:00 Complications Of A Heart Attack 00:00 Emergency Care For A Heart Attack Emergency Care For A Heart Attack 00:00 Risk Factors & Lifestyle Choices Risk Factors For Heart Disease 00:00 Lifestyle Choices For Your Heart 00:00 Heart Remedies Remedies For A Healthy Heart 00:00 Final Tips & Suggestions Conclusion - Final Tips & Suggestions 00:00

CardioWellness: Nurturing Heart Health
Delivered Online On Demand1 hour 10 minutes
£25

Pharmacology Diploma

4.5(3)

By Studyhub UK

Pharmacology is a critical field that directly impacts patient care and healthcare outcomes. This Pharmacology Diploma course is designed to provide a comprehensive understanding of pharmacology, from the fundamental principles to specific areas such as neuropharmacology, cardiovascular pharmacology, and more. By enrolling in this course, you will improve your knowledge and skills, ultimately enhancing your job performance and career prospects.   The Pharmacology Diploma course curriculum is meticulously crafted to ensure that you gain not only theoretical knowledge but also practical insights that are applicable in real-world scenarios. Extensive curriculum that includes fundamental principles of pharmacology, drug development and regulation, neuropharmacology, cardiovascular pharmacology, endocrine pharmacology, chemotherapy, inflammation and immune pharmacology, and toxicology. Whether you are a healthcare professional or someone looking to enter the field of pharmacology, this course will provide you with the tools you need to succeed.   This Pharmacology Diploma course is ideal for those who are keen to expand their knowledge and keep abreast of the latest developments in pharmacology. With the rapidly evolving nature of drugs and treatments, this course will keep you at the forefront of the field, enabling you to make informed decisions and provide optimal care to your patients.   Learning Outcomes Understand fundamental pharmacology principles. Comprehend drug development and regulatory processes. Gain insights into neuropharmacology and its applications. Understand cardiovascular pharmacology and related drugs. Grasp endocrine pharmacology's role in disease management. Learn about chemotherapy drugs and their mechanisms. Understand inflammation and immune pharmacology. Gain knowledge in toxicology and related safety measures. Apply pharmacology principles in practical scenarios. Evaluate drug interactions and their effects on patients.   Who is this course for Healthcare professionals seeking to expand their knowledge. Individuals aspiring to pursue a career in pharmacology. Researchers and academicians in the field of pharmacology. Pharmacy students looking for a comprehensive pharmacology resource. Anyone with an interest in understanding drug mechanisms and effects.   Why Choose This Course Unlimited access to the course for a lifetime. Opportunity to earn a certificate accredited by the CPD Quality Standards and CIQ after completing this course. Structured lesson planning in line with industry standards. Immerse yourself in innovative and captivating course materials and activities. Assessments designed to evaluate advanced cognitive abilities and skill proficiency. Flexibility to complete the Course at your own pace, on your own schedule. Receive full tutor support throughout the week, from Monday to Friday, to enhance your learning experience. Unlock career resources for CV improvement, interview readiness, and job success.   Career path Clinical Pharmacologist: £40,000 - £85,000 Pharmaceutical Researcher: £25,000 - £50,000 Pharmacology Educator: £30,000 - £45,000 Medical Science Liaison: £40,000 - £75,000 Regulatory Affairs Specialist: £30,000 - £60,000   Certification Upon completing the Pharmacology Diploma course materials, you have the option to take a written assignment test either during or at the course's conclusion. Successfully passing the test will allow you to claim a PDF certificate for £4.99. If you desire an Original Hard Copy certificate, it can be ordered for an additional £8.   Prerequisites This Pharmacology Diploma course has been crafted by industry professionals and is compatible with PCs, Macs, tablets, and smartphones. You can access the course from any location at any given time, provided you have a reliable internet connection. Course Curriculum Module 1: Fundamental Principles of Pharmacology Fundamental Principles of Pharmacology 00:23:00 Module 2: Drug Development and Regulation Drug Development and Regulation 00:15:00 Module 3: Neuropharmacology Neuropharmacology 00:15:00 Module 4: Cardiovascular Pharmacology Cardiovascular Pharmacology 00:20:00 Module 5: Endocrine Pharmacology Endocrine Pharmacology 00:22:00 Module 6: Chemotherapy Chemotherapy 00:19:00 Module 7: Inflammation and Immune Pharmacology Inflammation and Immune Pharmacology 00:14:00 Module 8: Toxicology Toxicology 00:17:00 Assignment Assignment - Pharmacology 00:00:00

Pharmacology Diploma
Delivered Online On Demand2 hours 25 minutes
£10.99

Educators matching "Cardiovascular"

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Pcsk9 Education And Research Forum

pcsk9 education and research forum

Alcester

Reducing low density lipoprotein (LDL) cholesterol is the priority in managing patients with severe dyslipidaemia (cholesterol abnormality) and at high risk of cardiovascular (CV) death and disability. Yet even when treated with potent statins, many patients fail to achieve LDL-cholesterol targets and therefore their risk of accelerated atherosclerosis and CV death remains high. This problem is particularly critical in patients with familial hypercholesterolaemia (FH) (the most commonly occurring genetic condition in the world). People with FH typically have very high LDL cholesterol levels on treatment, and consequently, are at very high risk of premature and sudden CV death, myocardial infarction and stroke. Additionally, some patients are unable to tolerate statins – particularly at higher doses – and, therefore, do not achieve LDL-cholesterol goals. What is the importance of PCSK9? Discovered in 2003,1 PCSK9 is a protein made by the liver which increases the removal of LDL receptors from the surface of liver cells. These LDL receptors are critically important in removal of serum LDL-cholesterol from the circulation. People with so-called ‘gain of function’ PCSK9 mutations over-express PCSK9, and therefore have very high plasma levels of LDL cholesterol and are at very risk of atherosclerosis and CV mortality and morbidity.2 In contrast, people with so-called ‘loss of function’ PCSK9 mutations, have very LDL cholesterol levels and reduced risk for heart disease.3 What is PCSK9 inhibition? Different approaches to lowering PCSK9 are now licensed. These include fully human monoclonal antibodies (alirocumab, evolocumab) and a small-interfering RNA therapy (inclisiran). Trials show that these PCSK9 inhibitors reduce LDL cholesterol levels by about 50-60 percent - a significantly greater effect than that achieved with currently available therapies – either when given alone or in combination. These LDL cholesterol lowering effects have been consistently across a broad group of patients, including those with familial hypercholesterolaemia in clinical trials.4 Which clinical settings will benefit from the availability of PCSK9 inhibitors? These treatments offer the potential to reduce cardiovascular risk in patients whose clinical needs cannot be satisfied by current therapy. These include: Patients with familial hypercholesterolaemia – an inherited disorder of lipid metabolism with a very high risk of early CV death or morbidity, if not diagnosed or treated early Patients who cannot tolerate statins, who therefore remain at high risk of CV events such as heart attacks and strokes Patients with established heart disease who have not achieved LDL-cholesterol goals despite current therapies