2712 Educators providing Research courses

pilates education and research ltd.

pcsk9 education and research forum

Reducing low density lipoprotein (LDL) cholesterol is the priority in managing patients with severe dyslipidaemia (cholesterol abnormality) and at high risk of cardiovascular (CV) death and disability. Yet even when treated with potent statins, many patients fail to achieve LDL-cholesterol targets and therefore their risk of accelerated atherosclerosis and CV death remains high. This problem is particularly critical in patients with familial hypercholesterolaemia (FH) (the most commonly occurring genetic condition in the world). People with FH typically have very high LDL cholesterol levels on treatment, and consequently, are at very high risk of premature and sudden CV death, myocardial infarction and stroke. Additionally, some patients are unable to tolerate statins – particularly at higher doses – and, therefore, do not achieve LDL-cholesterol goals. What is the importance of PCSK9? Discovered in 2003,1 PCSK9 is a protein made by the liver which increases the removal of LDL receptors from the surface of liver cells. These LDL receptors are critically important in removal of serum LDL-cholesterol from the circulation. People with so-called ‘gain of function’ PCSK9 mutations over-express PCSK9, and therefore have very high plasma levels of LDL cholesterol and are at very risk of atherosclerosis and CV mortality and morbidity.2 In contrast, people with so-called ‘loss of function’ PCSK9 mutations, have very LDL cholesterol levels and reduced risk for heart disease.3 What is PCSK9 inhibition? Different approaches to lowering PCSK9 are now licensed. These include fully human monoclonal antibodies (alirocumab, evolocumab) and a small-interfering RNA therapy (inclisiran). Trials show that these PCSK9 inhibitors reduce LDL cholesterol levels by about 50-60 percent - a significantly greater effect than that achieved with currently available therapies – either when given alone or in combination. These LDL cholesterol lowering effects have been consistently across a broad group of patients, including those with familial hypercholesterolaemia in clinical trials.4 Which clinical settings will benefit from the availability of PCSK9 inhibitors? These treatments offer the potential to reduce cardiovascular risk in patients whose clinical needs cannot be satisfied by current therapy. These include: Patients with familial hypercholesterolaemia – an inherited disorder of lipid metabolism with a very high risk of early CV death or morbidity, if not diagnosed or treated early Patients who cannot tolerate statins, who therefore remain at high risk of CV events such as heart attacks and strokes Patients with established heart disease who have not achieved LDL-cholesterol goals despite current therapies

pancreatic cancer uk

Support Line Freephone: 0808 801 0707. Dedicated UK pancreatic cancer charity. Specialist support. Investment in research. Driving awareness and change.

liverpool hope university business school

Liverpool Hope University pursues a path of excellence in scholarship and collegial life without reservation or hesitation. The University’s distinctive philosophy is to ‘educate in the round’ – mind, body and spirit – in the quest for Truth, Beauty and Goodness. No ordinary city, no ordinary university With a history extending 175 years, Liverpool Hope has developed a strong tradition of scholarship and research in key disciplines. Liverpool Hope has two main teaching campuses. Hope Park is situated in a leafy suburb of Liverpool and is a mini educational village. The Creative Campus in Liverpool city centre is the home to our creative and performing arts subjects. Both campuses have seen major investment in recent years, so traditional architecture now sits beside contemporary buildings and facilities. The University places great emphasis on the bringing together of research excellence and top-quality teaching. This is facilitated by a community of academics and scholars who are of the highest calibre. This research-informed teaching enables our students to develop into rounded and employable graduates who can take their place confidently as global citizens in the 21st century.

the software sustainability institute

About the Software Sustainability Institute Better software better research The Software Sustainability Institute motto. Cultivating research software to support world-class research Software is fundamental to research: 7 out of 10 researchers report their work would be impossible without it. From short, thrown-together temporary scripts to solving a specific problem, through an abundance of complex spreadsheets analysing collected data, to the hundreds of software engineers and millions of lines of code behind international efforts such as the Large Hadron Collider and the Square Kilometre Array, there are few areas of research where software does not have a fundamental role. Since 2010, the Software Sustainability Institute has facilitated the advancement of software in research by cultivating better, more sustainable, research software to enable world-class research (“Better software, better research”). In 2018, we were awarded funding from all seven research councils. Our mission is to become the world-leading hub for research software practice. The Institute is based at the Universities of Edinburgh, Manchester, Oxford and Southampton, and draws on a team of experts with a breadth of experience in software development, training, project and programme management, research facilitation, publicity and community engagement. The importance of sustainability Sustainability means that the software you use today will be available - and continue to be improved and supported - in the future. Expert knowledge Securing a future for research software requires more than just quality code, which is why, over the years, we have striven to help researchers build and use better software through better practices, and advocate for culture change within their communities and institutions. Building on our experience and expert understanding of the state of research software in the UK, our work focuses around four objectives: nurturing the growth of communities of practice to foster the sharing of expertise across the entire research community, conducting research to provide insight into the use of software in research, continuing enabling widespread adoption of research software practices, and offering training and guidance to help build a capable researcher community and increase the recognition of software in research.

the worldwide universities network

WUN is the world’s leading research university network, tackling global challenges through international collaboration.WUN brings together 24 leading comprehensive research universities in a collaborative partnership to advance research and education on major global challenges. Capitalizing on the geographical and cultural diversity of members across six continents, WUN enriches their shared experience, and brings together distinctive constellations of talent to address problems of real significance.

pennsylvania state university

The Pennsylvania State University is a multi-campus, land-grant, public research university that educates students from around the world and supports individuals and communities through integrated programs of teaching, research, and service. Our instructional mission includes undergraduate, graduate, professional, continuing, and extension education offered through both resident instruction and distance learning. Our educational programs are enriched by the talent, knowledge, diversity, creativity, and teaching and research acumen of our faculty, students, and staff.

the university of adelaide

There are many ways you can engage with us and our world-class educational and research activities. Collaborate to overcome a challenge. Apply our research to spark your innovation. Or give a financial gift to open more doors for the next generation.

dsm digital school of marketing

Digital School of Marketing The Digital School of Marketing (DSM) is South Africa’s preferred provider of accredited digital marketing education. Our educational institution is unique due to all of our marketing courses being accredited by (MICT SETA) the Media, Information and Communication Technologies Sector Education and Training Authority. In addition to this, we are a member of the IAB South Africa. DSM is also an endorsed member of the CPD Certification Service of the UK. Our courses are therefore internationally transferable and endorsed.

core africa

We believe research is the key to unlocking solutions to societal challenges in Africa… Promoting research equals promoting innovation and problem-solving